ericdane greysanatomy 290 'Grey's Anatomy' star Eric Dane hooks up with Christina Aguilera's 'Burlesque'Christina Aguilera‘s life is about to get McSteamier.

“Grey’s Anatomy” star Eric Dane is hopping into the tub, so to speak, with Aguilera and Cher for the former’s first big-screen lead role and the latter’s first non-animated role in a decade.

Dane will play a businessman out to buy Cher’s title burlesque and, at the same time, win Aguilera’s heart, according to The Hollywood Reporter.

Singer Aguilera will play a small-town girl who heads to Los Angeles to make her fortune, finding it at a club run by Cher while vying against rival Kristen Bell.

Filming began last week in Los Angeles for a Thanksgiving 2010 release.

Dane, meanwhile, is also known for toying with two women thanks to a sex tape he made with wife Rebecca Gayheart and former Playboy model Kari Anne Peniche.

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Posted by:Andy Grieser