joseph gordon levitt 320 Joseph Gordon Levitt cures James McAvoy of cancer comedyJoseph Gordon-Levitt has had a great past 12 months.

He starred in the summer breakout hit “500 Days of Summer,” the blockbuster “G.I. Joe: The Rise of Cobra,” shot Christopher Nolan’s thriller “Inception” and was the saving grace of Sundance pickup “Hesher.”  Now, Gordon-Levitt is stepping in at the last minute as the lead character in a new Jonathan Levine’s new untitled cancer comedy.

Levitt is replacing James McAvoy who, according to distributor Summit Entertainment, had to drop out “due to unrelated circumstances beyond his control.” Whether that really means “family matters” or he got sucked into another movie via contract is unclear.  At the moment, it is allowing Gordon-Levitt to join an intriguing cast including Best Supporting Actress nominee Anna Kendrick, Bryce Dallas Howard, Anjelica Huston, Philip Baker Hall and Seth Rogen. 

Based on screenwriter Will Reiser’s true life story, the film follows a twentysomething man who discovers he has cancer. 

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