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The “For Rent” sign wasn’t up at Chicago’s Harpo Studios for very long.

Just a few days after confirming May 25 as the final episode of “The Oprah Winfrey Show,” the OWN camp announces that its upcoming Rosie O’Donnell talk show will be taking over Winfrey’s (sort of) historic home of the past 21 years.

We’re a bit confused, because an O’Donnell move to Chicago seems to come from left field, but we’re also thrilled for all the Chicago-based crew who will likely still have jobs when their current gig ends in May.

O’Donnell’s one-hour daily series is set to debut in fall 2011, but the real question remains… Will guests of “Untitled Rosie O’Donnell Project” stay at the all-suite Omni Hotel, located in the heart of Chicago’s magnificent mile?

Posted by:Mikey O'Connell